Publications
Selected papers
2023
Nisi Zhang, Yutong Guo, Josquin Foiret, Spencer K Tumbale, Ramasamy Paulmurugan, Katherine W Ferrara. “Protocol for in vitro sonoporation validation using non-targeted microbubbles for human studies of ultrasound-mediated gene delivery.” STAR protocols, 2023 Dec. 15; 4 (4):102723. doi: 10.1016/j.xpro.2023.102723.
Zhang N, Zeng W, Xu Y, Li R, Wang M, Liu Y, Qu S, Ferrara KW, Dai Z. “Pyroptosis Induction with Nanosonosensitizer-Augmented Sonodynamic Therapy Combined with PD-L1 Blockade Boosts Efficacy against Liver Cancer.” Adv Healthc Mater., 2023 Nov. 21; 13(7): e2302606. doi: 10.1002/adhm.202302606. PMID: 37987462.
Pei Liu, Josquin Foiret, Yinglin Situ, Nisi Zhang, Aris J. Kare, Bo Wu, Marina N. Raie, Katherine W. Ferrara & Lei S. Qi. “Sonogenetic control of multiplexed genome regulation and base editing.” Nat Commun, 2023 Oct. 18; 14 (6575): doi: 10.1038/s41467-023-42249-8.
Tatiana Khokhlova; Yak-Nam Wang; Helena Son; Zhen Xu; Reliza McGinnis; Brett Fite; Aris Kare; Katherine Ferrara; Frederic Padilla. “Characterization of acute and subacute immune response to boiling histotripsy ablation of pancreatic adenocarcinoma.” The Journal of the Acoustical Society of America, 2023 Oct. 1; 154 (4_supplement): A278. doi: 10.1121/10.0023518.
Aris J. Kare, Lisa Nichols, Ricardo Zermeno, Marina N. Raie, Spencer K. Tumbale, Katherine W. Ferrara. “OMIP-095: 40-Color spectral flow cytometry delineates all major leukocyte populations in murine lymphoid tissues.” Cytometry Part A., 2023 Sept. 28; 1–12. doi: 10.1002/cyto.a.24788.
Javier Ajenjo, Jai Woong Seo, Josquin Foiret, Bo Wu, Marina Nura Raie, James Wang, Brett Zain Fite, Nisi Zhang, Rim Malek, Corinne Beinat, Noeen Malik, David Alexander Anders, Katherine W Ferrara. “PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain.” Theranostics., 2023 Sept. 25; 13 (15): 5151-5169. doi: 10.7150/thno.85549. PMID: 37908737; PMCID: PMC10614693.
Martin Karl Schneider, James Wang, Aris Kare, Shaunak S Adkar, Darren Salmi, Caitlin F Bell, Tom Alsaigh, Dhananjay Wagh, John Coller, Aaron Mayer, Sarah J Snyder, Alexander D Borowsky, Steven R Long, Maarten G Lansberg, Gary K Steinberg, Jeremy J Heit, Nicholas J Leeper, Katherine W Ferrara. “Combined near infrared photoacoustic imaging and ultrasound detects vulnerable atherosclerotic plaque.” Biomaterials, 2023 Sept. 11; 122314. doi: 10.1016/j.biomaterials.2023.122314.
James Zengel, Yu Xin Wang, Jai Woong Seo, Ke Ning, James N Hamilton, Bo Wu, Marina Raie, Colin Holbrook, Shiqi Su, Derek R Clements, Sirika Pillay, Andreas S Puschnik, Monte M Winslow, Juliana Idoyaga, Claude M Nagamine, Yang Sun, Vinit B Mahajan, Katherine W Ferrara, Helen M Blau, Jan E Carette. “Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.” Nature Methods. 2023 Jun. 8; 20:1070–1081. doi: 10.1038/s41592-023-01896-x.
Eun-Yeong Park, Xiran Cai, Josquin Foiret, Hanna Bendjador, Dongwoon Hyun, Brett Z Fite, Robert Wodnicki, Jeremy J Dahl, Robert D Boutin, Katherine W Ferrara. “Fast volumetric ultrasound facilitates high-resolution 3D mapping of tissue compartments.” American Association for the Advancement of Science. 2023 May 31. doi: 10.1126/sciadv.adg8176.
Rifat Ahmed, Josquin Foiret, Katherine Ferrara, Gregg Trahey. “Large Array Deep Abdominal Imaging in Fundamental and Harmonic Mode. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.” 2023 Mar. 10; 70(3):406-421. doi: 10.1109/TUFFC.2023.3255800. PMID: 37028314.
Jung Ho Yu, Myeong Seon Jeong, Emma Olivia Cruz, Israt S Alam, Spencer K Tumbale, Aimen Zlitni, Song Yeul Lee, Yong Il Park, Katherine Ferrara, Seung-Hae Kwon, Sanjiv S Gambhir, Jianghong Rao. “Highly Excretable Gold Supraclusters for Translatable In Vivo Raman Imaging of Tumors.” ACS Nano. 2023 Jan. 23; 17(3):2554-2567. doi: 10.1021/acsnano.2c10378.
2022
J Wang, BZ Fite, AJ Kare, B Wu, M Raie, SK Tumbale, N Zhang, RR Davis, CG Tepper, S Aviran, AM Newman, DA King, KW Ferrara. “Multiomic analysis for optimization of combined focal and immunotherapy protocols in murine pancreatic cancer.” Theranostics. 2022 Nov 14; 12(18): 7884-7902. doi: 10.7150/thno.73218. PMID: 36451859; PMCID: PMC9706583.
R Wodnicki, H Bendjador, H Kang, J Foiret, C Notard, Q Zhou, K W Ferrara “Row-Multiplexed 1,024 Element Large Aperture Array for Electronic Scanning in Elevation.” 2022 IEEE International Ultrasonics Symposium (IUS), 2022 Oct., pp. 1-4, doi: 10.1109/IUS54386.2022.9958124.
H Bendjador, J Foiret, R Wodnicki, K Ferrara. “Deep high resolution 4D ultrafast ultrasound imaging with 2D matrix arrays.” Bulletin of the American Physical Society. 2022 March.
W Chen, L Xu, E Chang, G Gowrishankar, KW Ferrara, SS Gambhir. “Alternative medicine: therapeutic effects on gastric original signet ring carcinoma via ascorbate and combination with sodium alpha lipoate.” BMC Complementary Medicine and Therapies. 2022 March; 22 (58): 1-11. doi: 10.1186/s12906-022-03541-0.
Jai Woong Seo, Javier Ajenjo, Bo Wu, Elise Robinson, Marina Nura Raie, James Wang, Spencer K Tumbale, Pablo Buccino, David Alexander Anders, Bin Shen, Frezghi G Habte, Corinne Beinat, Michelle L James, Samantha Taylor Reyes, Ravindra Kumar Sripriya, Timothy F Miles, Jason T Lee, Viviana Gradinaru, Katherine W Ferrara. “Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs.” Biomaterials. 2022; 121701. doi: 10.1016/j.biomaterials.2022.121701.
J Foiret, X Cai, H Bendjador, EY Park, A Kamaya, KW Ferrara. “Improving plane wave ultrasound imaging through real-time beamformation across multiple arrays.” Scientific Reports. 2022; 12 (1): 1-14. doi: 10.1038/s41598-022-16961-2.
Robert Wodnicki, Haochen Kang, Di Li, Douglas N. Stephens, Hayong Jung, Yizhe Sun, Ruimin Chen, Lai-Ming Jiang, Nestor E. Cabrera-Munoz, Josquin Foiret, Qifa Zhou, Katherine W. Ferrara. “Highly Integrated Multiplexing and Buffering Electronics for Large Aperture Ultrasonic Arrays.” BME frontiers. 2022; Article ID 9870386: 1-22. doi: 10.34133/2022/9870386.
Elise R. Robinson, Aris J. Kare, Azadeh Kheirolomoom, Mohammed Inayathullah, Spencer K. Tumbale, Bo Wu, Marina N. Raie, Jai W. Seo, Felix B. Salazar, Ramasamy Paulmurugan, Anna M. Wu, Katherine W. Ferrara. “CD3 and CD8 targeting of ionizable lipid nanoparticles for in vivo mRNA delivery to T cells.” Cancer Research. 2022; 82 (12_Supplement): 5372. doi: 10.1158/1538-7445.AM2022-5372.
Wang J, Fite BZ , Kare A, Wu B, Raie MN, Tumbale S, Davis RR, Tepper CG, Ferrara K. “TME subtype impacts response to combined thermal ablation and immunotherapy.” Cancer Research. 2022; 82 (12_Supplement): 6314. doi: 10.1158/1538-7445.AM2022-6314.
Fite BZ, Wang J, Ghanouni P, Ferrara KW. “A review of imaging methods to assess ultrasound-mediated ablation.” AAAS BME Frontiers. 2022 May; Article ID 9758652: 1-17. doi: 10.34133/2022/9758652.
Kheirolomoom A, Kare AJ, Ingham ES, Paulmurugan R, Robinson ER, Baikoghli M, Inayathullah M, Seo JW, Wang J, Fite BZ, Wu B, Tumbale SK, Raie MN, Cheng RH, Nichols L, Borowsky AD, Ferrara KW. “In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift.” Biomaterials. 2022 Feb; 281: 121339. doi: 10.1016/j.biomaterials.2021.121339.
Bendjador H, Foiret J, Wodnicki R, Stephens DN, Krut Z, EY Park, Gazit Z, Gazit D, Pelled G, Ferrara KW. “A theranostic 3D ultrasound imaging system for high resolution image-guided therapy.” Theranostics. 2022 Jun 27; 12 (11): 4949. doi: 10.7150/thno.71221.
2021
US Kumar, R Afjei, K Ferrara, TF Massoud, R Paulmurugan. “Gold-nanostar-chitosan-mediated delivery of SARS-CoV-2 DNA vaccine for respiratory mucosal immunization: Development and proof-of-principle.”
ACS nano. 2021 Oct. 28;15(11):17582-17601. doi: 10.1021/acsnano.1c05002.
Robert Wodnicki, Haochen Kang, Junhang Zhang, Josquin Foiret, Christophe Notard, Leong Ratsimandresy, Philippe Auclair, Qifa Zhou, Katherine W Ferrara. “Modular Large Array for Liver Cancer Imaging in Handheld Form Factor.” 2021 IEEE International Ultrasonics Symposium (IUS). 2021 Sept.:1-4. doi: 10.1109/IUS52206.2021.9593539.
Nisi Zhang,Josquin Foiret,Azadeh Kheirolomoom,Pei Liu,Yi Feng,Spencer Tumbale,Marina Raie,Bo Wu,James Wang,Brett Z. Fite,Zhifei Dai,Katherine W. Ferrara. “Optimization of Microbubble‐Based DNA Vaccination with Low‐Frequency Ultrasound for Enhanced Cancer Immunotherapy.” Advanced therapeutics. 2021 Sept.;4(9): 2100033. doi: 10.1002/adtp.202100033
Zhang N, Foiret J, Kheirolomoom A, Liu P, Feng Y, Tumbale S, Raie M, Wu B, Wang J, Fite BZ, Dai Z, Ferrara KW. “Optimization of Microbubble‐Based DNA Vaccination with Low‐Frequency Ultrasound for Enhanced Cancer Immunotherapy.” Advanced Therapeutics. 2021;4(9). https://doi.org/10.1002/adtp.202100033.
Aghevlian S, Wu B, Raie MN, Tumbale SK, Kare AJ, Seo JW, Ferrara KW, “Pre-clinical evaluation of immunoPET imaging using agonist CD40 monoclonal antibody in pancreatic tumor-bearing mice,” Nuclear Medicine and Biology, Nucl Med Biol. 2021;98-99: 8-17. doi: 10.1016/j.nucmedbio.2021.04.001. PMID: 33962357.
Brandner DM, Cai X, Foiret J, Ferrara KW, Zagar BG, “Estimation of Tissue Attenuation from Ultrasonic B-Mode Images-Spectral-Log-Difference and Method-of-Moments Algorithms Compared,” Sensors (Basel), 2021; 21(7). doi: 10.3390/s21072548. PMID: 33916496; PMCID: PMC8038607.
Fite BZ, Wang J, Kare AJ, Ilovitsh A, Chavez M, Ilovitsh T, Zhang N, Chen W, Robinson E, Zhang H, Kheirolomoom A, Silvestrini MT, Ingham ES, Mahakian LM, Tam SM, Davis RR, Tepper CG, Borowsky AD, Ferrara KW, “Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer,” Scientific Reports, Sci Rep. 2021; 11(1): 927. doi: 10.1038/s41598-020-80135-1. PMID: 33441763; PMCID: PMC7806949.
Kakwere H, Zhang H, Ingham ES, Nura-Raie M, Tumbale SK, Allen R, Tam SM, Wu B, Liu C, Kheirolomoom A, Fite BZ, Ilovitsh A, Lewis JS, Ferrara KW, “Systemic Immunotherapy with Micellar Resiquimod-Polymer Conjugates Triggers a Robust Antitumor Response in a Breast Cancer Model,” Advanced Healthcare Materials, Adv Healthc Mater. 2021; 10(10): e2100008. doi: 10.1002/adhm.202100008. PMID: 33646600; PMCID: PMC8153207.
Robinson ER, Gowrishankar G, D’Souza AL, Kheirolomoom A, Haywood T, Hori SS, Chuang HY, Zeng Y, Tumbale SK, Aalipour A, Beinat C, Alam IS, Sathirachinda A, Kanada M, Paulmurugan R, Ferrara KW, Gambhir SS, “Minicircles for a two-step blood biomarker and PET imaging early cancer detection strategy,” Journal of Controlled Release, J Control Release. 2021; 335: 281-9. doi: 10.1016/j.jconrel.2021.05.026. PMID: 34029631; PMCID: PMC8262353.
Stephens DN, Wodnicki R, Chen R, Liang LM, Zhou Q, Morrison K, Ferrara KW, “The effective coupling coefficient for a completed PIN-PMN-PT array,” Ultrasonics, 2021; 109: 106258. doi: 10.1016/j.ultras.2020.106258. PMID: 33011614; PMCID: PMC7744335.
Zhang H, Tang WL, Kheirolomoom A, Fite BZ, Wu B, Lau K, Baikoghli M, Raie MN, Tumbale SK, Foiret J, Ingham ES, Mahakian LM, Tam SM, Cheng RH, Borowsky AD, Ferrara KW, “Development of thermosensitive resiquimod-loaded liposomes for enhanced cancer immunotherapy,” Journal of Controlled Release, J Control Release. 2021; 330: 1080-94. doi: 10.1016/j.jconrel.2020.11.013. PMID: 33189786; PMCID: PMC7906914.
Zhang N, Wang J, Foiret J, Dai Z, Ferrara KW, “Synergies between therapeutic ultrasound, gene therapy and immunotherapy in cancer treatment,” Advanced Drug Delivery Reviews, Adv Drug Deliv Rev. 2021:113906. doi: 10.1016/j.addr.2021.113906. PMID: 34333075.
2020
Ilovitsh T, Feng Y, Foiret J, Kheirolomoom A, Zhang H, Ingham ES, Ilovitsh A, Tumbale SK, Fite BZ, Wu B, Raie MN, Zhang N, Kare AJ, Chavez M, Qi LS, Pelled G, Gazit D, Vermesh O, Steinberg I, Gambhir SS, Ferrara KW, “Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites,” Proceedings of the National Academy of Sciences of the U S A, Proc Natl Acad Sci U S A (PNAS). 2020; 117(23): 12674-85. doi: 10.1073/pnas.1914906117. PMID: 32430322; PMCID: PMC7293655.
Kakwere H, Ingham ES, Tumbale SK, Ferrara KW, “Gemcitabine-retinoid prodrug loaded nanoparticles display in vitro antitumor efficacy towards drug-resilient human PANC-1 pancreatic cancer cells,” Materials Science and Engineering: C, Mater Sci Eng C (Mater Biol Appl). 2020; 117: 111251. doi: 10.1016/j.msec.2020.111251. PMID: 32919625; PMCID: PMC7684797.
Seo JW, Ingham ES, Mahakian L, Tumbale S, Wu B, Aghevlian S, Shams S, Baikoghli M, Jain P, Ding X, Goeden N, Dobreva T, Flytzanis NC, Chavez M, Singhal K, Leib R, James ML, Segal DJ, Cheng RH, Silva EA, Gradinaru V, Ferrara KW, “Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation,” Nature Communications, Nat Commun. 2020; 11(1): 2102. doi: 10.1038/s41467-020-15818-4. PMID: 32355221; PMCID: PMC7193641.
Wang Z, Xue X, Lu H, He Y, Lu Z, Chen Z, Yuan Y, Tang N, Dreyer CA, Quigley L, Curro N, Lam KS, Walton JH, Lin TY, Louie AY, Gilbert DA, Liu K, Ferrara KW, Li Y, “Two-way magnetic resonance tuning and enhanced subtraction imaging for non-invasive and quantitative biological imaging,” Nature Nanotechnology, Nat Nanotechnol. 2020; 15(6): 482-90. doi: 10.1038/s41565-020-0678-5. PMID: 32451501; PMCID: PMC7307456.
Wodnicki R, Kang H, Chen R, Cabrera-Munoz NE, Jung H, Jiang L, Foiret J, Liu Y, Chiu V, Stephens DN, Zhou Q, Ferrara KW, “Co-Integrated PIN-PMN-PT 2-D Array and Transceiver Electronics by Direct Assembly Using a 3-D Printed Interposer Grid Frame,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 2020; 67(2): 387-401. doi: 10.1109/TUFFC.2019.2944668. PMID: 31567082; PMCID: PMC6992507.
2019
Ilovitsh A, Ilovitsh T, Foiret J, and Ferrara KW, “Simultaneous Axial Multifocal Imaging Using a Single Acoustical Transmission: A Practical Implementation,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 2019 Feb; 66(2): 273-284. doi: 10.1109/TUFFC.2018.2885080. PMC6375789.
Bez M, Foiret J, Shapiro G, Pelled P, Ferrara KW, Gazit D, “Nonviral ultrasound-mediated gene delivery in small and large animal models,” Nature Protocols, 2019 Feb 25. doi: 10.1038/s41596-019-0125-y.
Zhong, Q, Yoon BC, Aryal M, Wang JB, Ilovitsh T, Nassab N, Karthik A, Ferrara KW, Airan RD, “Polymeric perfluorocarbon nanoemulsions are ultrasound-activated wireless drug infusion catheters,” Biomaterials. 2019 Mar 20; 206: 73-86. doi: 10.1016/j.biomaterials.2019.03.021. PMC6486876.
Sundstrøm T, Prestegarden L, Azuaje F, Aasen SN, Røsland GV, Varughese JK, Marzieh Bahador M, Bernatz S, Braun Y; Harter PN, Skaftnesmo KO, Ingham ES, Mahakian LM, Tam SM, Tepper C, Petersen K, Ferrara KW, Tronstad KJ, Lund-Johansen M, Beschorner R, Bjerkvig R, Thorsen FA, “Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis,” Acta Neuropathologica Communications, Acta Neuropathol Commun. 2019 Apr 10; 7(1): 55. doi: 10.1186/s40478-019-0712-8. PMC6456988.
Azadeh Kheirolomoom, Matthew T. Silvestrini, Elizabeth S. Ingham, Lisa M. Mahakian, Sarah M. Tam, Spencer K. Tumbale, Josquin Foiret, Neil E. Hubbard, Alexander D. Borowsky, Ferrara KW, “Combining activatable nanodelivery with immunotherapy in a murine breast cancer model,”
Journal of Controlled Release, J Control Release. 2019 Apr 9. pii: S0168-3659(19)30202-0. doi: 10.1016/j.jconrel.2019.04.008.
Ilovitsh A, Fite BZ, Ferrara KW, “Magnetic Resonance Elastography using Focused Ultrasound and Multishot Spiral Readout,” Physics in Medicine & Biology, Phys Med Biol (PMB). epub 2019 Apr 29, doi: 10.1088/1361-6560/ab1e21
Tucci ST, Kheirolomoom A, Ingham ES, Baikoghli M, Cheng RH, Neil E. Hubbard, Alexander D. Borowsky, Ferrara KW, “Tumor-specific delivery of gemcitabine with activatable liposomes,” Journal of Controlled Release, J Control Release. 2019 Jul 10. pii: S0168-3659(19)30401-8. doi: 10.1016/j.jconrel.2019.07.014, PMC6815719.
Ilovitsh A, Ilovitsh T, and Ferrara KW, “Multiplexed ultrasound beam summation for side lobe reduction,” Scientific Reports, Sci Rep. 2019 Sep 27; 9(1): 13961. doi: 10.1038/s41598-019-50317-7.
Wodnicki R, Kang H, Chen R, Cabrera-Munoz NE, Jong H, Jiang L, Foiret J, Liu Y, Chiu V, Stephens DN, Zhou Q, Ferrara KW, “Co-integrated PIN-PMN-PT 2D Array and Transceiver Electronics by Direct-Assembly Using a 3D Printed Interposer Grid Frame,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 2019 Sep 30. doi: 10.1109/TUFFC.2019.2944668.
Yeow Y, Kotamraju V, Wang J, Chopra M, Azme N, Wu S, Schoep TD, Delaney DS, Feindel K, Li K, Kennedy K, Allen W, Kennedy B, Larma I, Sampson D, Mahakian LM, Fite BZ, Zhang H, Friman T, Mann A, Aziz FA, Kumarasinghe MP, Johansson M, Fe HC, Yeoh G, Mou L, Ferrara KW, Billiran H, Ganss R, Ruoslahti E, Hamzah J, “Immune‐mediated ECM depletion improves tumour perfusion and payload delivery,” EMBO Molecular Medicine, EMBO Mol Med (2019)e10923, https://doi.org/10.15252/emmm.201910923.
Cai X, Foiret J, Roth J, Gazit Z, Pelled G, Gazit D, Ferrara KW, “3D monitoring and control of microbubble cavitation for gene delivery,” 2019 IEEE International Ultrasonics Symposium (IUS); 2019 6-9 Oct. 2019. 10.1109/ULTSYM.2019.8926184.
Foiret J, Seo JW, Zhang H, Kakwere H, Mahakian LM, Tam S, Ferrara KW, “Enhanced delivery of AAV-like nanoparticles after blood-brain barrier disruption in a mouse model, 2019 IEEE International Ultrasonics Symposium (IUS). 2019 6-9 Oct. 2019. 10.1109/ULTSYM.2019.8925683.
Wodnicki R, Kang H, Li D, Sun Y, Jiang L, Chen R, Chen Z, Jong H, Foiret J, Liu Y, Chiu V, Stephens DN, Zhou Q, Ferrara KW, “Tiled Large Element 1.75D Aperture with Dual Array Modules by Adjacent Integration of PIN-PMN-PT Transducers and Custom High Voltage Switching ASICs,” 2019 IEEE International Ultrasonics Symposium (IUS). 2019 6-9 Oct. 2019. 10.1109/ULTSYM.2019.8925552.
2018
Ilovitsh T, Ilovitsh A, Foiret J, Fite BZ, and Ferrara KW, “Acoustical structured illumination for super-resolution ultrasound imaging,” Communications Biology, (a new Nature Journal), volume 1, Article number: 3 (2018) doi:10.1038/s42003-017-0003-5, PMC5988254.
Ilovitsh T, Ilovitsh I, Foiret J, and Ferrara KW, “Imaging beyond ultrasonically-impenetrable objects,” Scientific Reports, Sci Rep. 2018 Apr 10;8(1):5759. doi: 10.1038/s41598-018-23776-7, PMC5893560.
Bez M, Kremen TJ, Tawackoli W, Sheyn D, Shapiro G, Giaconi JC, Ferrara KW, Gazit D, Pelled G, “Ultrasound-mediated Gene Delivery Enhances Tendon Allograft Integration in Mini-pig Ligament Reconstruction,” Molecular Therapy, Mol Ther. 2018 Jul 5; 26(7): 1746-1755. doi: 10.1016/j.ymthe.2018.04.020. pii: S1525-0016(18)30193-X, PMC6035740.
Seo JW, Mahakian LM, Silvestrini MT, Tam S, Ingham ES, Salazar FB, Borowsky AD, Wu AM, and Ferrara KW, “CD8+ T-cell Density Imaging with 64Cu-labeled Cys-Diabody Informs Immunotherapy Protocols,” Clinical Cancer Research, Clin Cancer Res. 2018 Jul 2. pii: clincanres.0261.2018. doi: 10.1158/1078-0432.CCR-18-0261, PMC6215696.
Chavez M, Silvestrini MT, Ingham ES, Fite BZ, Mahakian LM, Tam SM, Ilovitsh A, Monjazeb AM, Murphy WJ, Hubbard NE, Davis RR, Tepper CG, Borowsky AD, Ferrara KW, “Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation,” Theranostics 2018; 8(13): 3611-3628. doi:10.7150/thno.25613, PMC6037035.
Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS and Ferrara KW, “Unimicellar hyperstars as multi-antigen cancer nanovaccines displaying clustered epitopes of immunostimulating peptides,” Royal Society of Chemistry Biomaterials Science, RSC Biomater Sci. 2018 Sep 19. doi: 10.1039/c8bm00891d, PMC6261306.
Tucci ST, Seo JW, Kakwere H, Kheirolomoom A, Ingham ES, Baikoghli M, Cheng RH, Ferrara KW, “A scalable method for squalenoylation and assembly of squalenoylated gemcitabine-64Cu-nanoparticles,” Nanotheranostics, 2018; 2(4): 387-402. doi:10.7150/ntno.26969, PMC6170330.
Ilovitsh T, Ilovitsh A, Foiret J, Caskey CF, Kusunose J, Fite BZ, Zhang H, Mahakian LM, Tam S, Butts-Pauly K, Qin S, Ferrara KW, “Enhanced microbubble contrast agent oscillation following 250 kHz insonation,” Scientific Reports, Sci Rep. 2018 Nov 5; 8(1): 16347, doi: 10.1038/s41598-018-34494-5, PMC6218550.
Stephens D.N., Wodnicki R, Chen R., Liang L.-M., Zhou Q., Morrison K., Ferrara KW, “Assessment of Electromechanical Coupling Coefficient for a Completed PIN-PMN-PT Array,” 2018 IEEE International Ultrasonics Symposium (IUS). 2018, pp. 1-4. doi: 10.1109/ULTSYM.2018.8580004.
Robert Wodnicki, Haochen Kang, Jayesh Adhikari, Rui Zhang, Ruimin Chen, Laiming Jiang, Nestor Cabrera-Munoz, Yu Liu, Victoria Chiu, Hayong Jung, Josquin Foiret, Qifa Zhou, Douglas N. Stephens, Ferrara KW, “Modular Fabrication and Assembly of Large 2D Arrays with Interface ASICs, PIN-PMN-PT Composite, and 3D Printed Backing,” 2018 IEEE International Ultrasonics Symposium (IUS), won student paper award, 2018, pp. 1-4. doi: 10.1109/ULTSYM.2018.8579640.
2017
Foiret J, Zhang H, Mahakian LM, Tam S, Ilovitsh T, Ferrara KW, “Ultrasound localization microscopy to image and assess microvasculature in a rat kidney,” Scientific Reports, Sci Rep. 2017 Oct 20; 7(1): 13662. doi: 10.1038/s41598-017-13676-7. PMC5651923.
Kakwere H, Ingham ES, Allen R, Mahakian LM, Tam SM, Zhang H, Silvestrini MT, Lewis JS and Ferrara KW, “Towards Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach,” Bioconjugate Chemistry, 2017 Nov 15; 28(11): 2756-2771. doi: 10.1021/acs.bioconjchem.7b00502. Epub 2017 Oct 13. PMC5687982.
Bez M, Sheyn D, Tawackoli W, Avalos P, Shapiro G, Giaconi JC, Da X, David SB, Gavrity J, Awad HA, Bae HW, Ley EJ, Kremen TJ, Gazit Z, Ferrara KW, Pelled G, Gazit D. “In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs,” Science Translational Medicine, Sci Transl Med. 2017 May 17; 9(390). pii: eaal3128. doi: 10.1126/scitranslmed.aal3128.
Also see this science magazine article about how Tiny Bubbles and Gene Therapy Heal Bone Fractures in Pigs.
Baikejiang R, Zhao Y, Fite BZ, Ferrara KW, Li C, “Anatomical image-guided fluorescence molecular tomography reconstruction using kernel method,” Journal of Biomedical Optics, J Biomed Opt. 2017 May 1; 22(5): 55001. doi: 10.1117/1.JBO.22.5.055001.
Silvestrini MT, Ingham ES, Mahakian LM, Kheirolomoom A, Liu Y, Fite BZ, Tam SM, Tucci ST, Watson KD, Wong AW, Monjazeb AM, Hubbard NE, Murphy WJ, Borowsky AD, Ferrara KW, “Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols,” The Journal of Clinical Investigation Insight, JCI Insight. 2017 Mar 23; 2(6): e90521. doi: 10.1172/jci.insight.90521.
Foiret J, Zhang H, Fite BZ, Mahakian L, Tam S, Segal DJ, Ferrara KW, “Blood-brain barrier disruption for the delivery of non-infectious viral vectors and proteins, preliminary study,” 2017 IEEE International Ultrasonics Symposium (IUS), in process. doi: 10.1109/ULTSYM.2017.8092207.
Robert Wodnicki, Haochen Kang, Rui Zhang, Nestor Cabrera Munoz, Ruimin Chen, Chi Tat Chiu, Qifa Zhou, Douglas N. Stephens, Ferrara KW, “PIN-PMN-PT single crystal composite and 3D printed interposer backing for ASIC integration of large aperture 2D array,” 2017 IEEE International Ultrasonics Symposium (IUS), in process. doi: 10.1109/ULTSYM.2017.8091685.
Liu Y, Liu J, Fite BZ, Foiret J, Ilovitsh A, Leach JK, Dumont E, Caskey CF, Ferrara KW, “Supersonic transient magnetic resonance elastography for quantitative assessment of tissue elasticity,” Physics in Medicine & Biology, Phys Med Biol (PMB). 2017 Apr 20; 62(10): 4083-4106. doi: 10.1088/1361-6560/aa6674. [Epub ahead of print].
Fite BZ, Kheirolomoom A, Foiret JL, Seo JW, Mahakian LM, Ingham ES, Tam SM, Borowsky AD, Curry FE, Ferrara KW, “Dynamic contrast enhanced MRI detects changes in vascular transport rate constants following treatment with thermally-sensitive liposomal doxorubicin,” Journal of Controlled Release, J Control Release. 2017 Apr 7. pii: S0168-3659(17)30518-7. doi: 10.1016/j.jconrel.2017.04.007. [Epub ahead of print].
Pollard RE, Watson KD, Hu X, Ingham E, Ferrara KW, “Feasibility of quantitative contrast ultrasound imaging of bladder tumors in dogs,” The Canadian Veterinary Journal, Can Vet J. 2017 Jan;58(1):70-72. PMID: 28042158. PMCID: PMC5157742.
Zhang H, Ingham ES, Gagnon MK, Mahakian LM, Liu J, Foiret JL, Willmann JK, Ferrara KW, “In vitro characterization and in vivo ultrasound molecular imaging of nucleolin-targeted microbubbles,” Biomaterials, 2017 Feb;118:63-73. doi: 10.1016/j.biomaterials.2016.11.026. Epub 2016 Nov 21.
2016
Kheirolomoom A, Ingham ES, Commisso J, Abushaban N, Ferrara KW, “Intracellular trafficking of a pH-responsive drug metal complex,” Journal of Controlled Release, J Control Release. 2016 Oct 13; 243: 232-242. doi: 10.1016/j.jconrel.2016.10.012
Foiret J, Zhang H, Mahakian LM, Tam SM, Ferrara KW, “Super-localization of contrast agents in moving organs, first experiments in a rat kidney,” 2016 IEEE International Ultrasonics Symposium (IUS).
Liu Y, Liu J, Fite BZ, Foiret J, Leach JK, Ferrara KW, “Quantitative MR-guided transient shear wave imaging for tissue elasticity assessment,” 2016 IEEE International Ultrasonics Symposium (IUS) Proceedings. doi: 10.1109/ULTSYM.2016.7728857.
Stephens DN, Foiret JL, Lucero S, Ferrara KW, Shivkumar K, Khuri-Yakub P, “HIFU Power Network Optimization for Catheter Based Cardiac Interventions,” 2016 IEEE International Ultrasonics Symposium (IUS) Proceedings. doi: 10.1109/ULTSYM.2016.7728834.
Liu J, Foiret J, Stephens DN, Le Baron O, Ferrara KW, “Development of a spherically focused phased array transducer for ultrasonic image-guided hyperthermia,” Physics in Medicine & Biology, Phys Med Biol (PMB). 2016 Jul 21; 61(14): 5275-96. doi: 10.1088/0031-9155/61/14/5275. Epub 2016 Jun 29.
Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann-Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan CX, “Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer,” Biomaterials, 2016 Oct;104:339-51. doi: 10.1016/j.biomaterials.2016.07.026. Epub 2016 Jul 22.
Shapiro G, Wong AW, Bez M, Yang F, Tam SM, Even LM, Sheyn D, Ben-David S, Tawackoli W, Pelled G, Ferrara KW, Gazit D, “Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation,” Journal of Controlled Release, J Control Release. 2016 Feb 10; 223: 157-64. doi: 10.1016/j.jconrel.2015.12.001. Epub 2015 Dec 10, PMC4724495.
Wong AW, Fite BZ, Liu Y, Kheirolomoom A, Seo JW, Watson KD, Mahakian LM, Tam SM, Zhang H, Foiret J, Borowsky AD, Ferrara KW, “Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models,” The Journal of Clinical Investigation, J Clin Invest. 2016 Jan;126(1):99-111. doi: 10.1172/JCI83312. Epub 2015 Nov 23, PMC4701551.
2015
Patel D, Gao Y, Son K, Siltanen C, Neve RM, Ferrara K, Revzin A, “Microfluidic co-cultures with hydrogel-based ligand trap to study paracrine signals giving rise to cancer drug resistance,” Lab on a Chip, Lab Chip. 2015 Dec 21; 15(24): 4614-24. doi: 10.1039/c5lc00948k. Epub 2015 Nov 6.
Kheirolomoom A, Ingham ES, Mahakian LM, Tam SM, Silvestrini MT, Tumbale SK, Foiret J, Hubbard NE, Borowsky AD, Murphy WJ, Ferrara KW, “CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery,” Journal of Controlled Release, J Control Release. pii: S0168-3659(15)30184-X. doi:10.1016/j.jconrel.2015.10.016. 2015 Oct 9.
Liu Y, Fite BZ, Mahakian LM, Johnson SM, Larrat B, Dumont E and Ferrara KW, “Concurrent Visualization of Acoustic Radiation Force Displacement and Shear Wave Propagation with 7T MRI,” Public Library of Science One, PLoS ONE 10(10): e0139667. doi:10.1371/journal.pone.0139667. 2015 Oct 6.
Seo JW, Ang J, Mahakian LM, Tam S, Fite BZ, Ingham ES, Beyer J, Forsayeth J, Bankiewicz KS, Xu T and Ferrara KW, “Self-assembled 20-nm 64Cu-micelles enhance accumulation in rat glioblastoma,” Journal of Controlled Release, J Control Release. pii: S0168-3659(15)30157-7. doi: 10.1016/j.jconrel.2015.09.057. 2015 Oct 2.
Kheirolomoom A, Kim CW, Seo JW, Kumar S, Son DJ, Gagnon MK, Ingham ES, Ferrara KW, Jo H, “Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE-/- Mice,” ACS Nano, 2015 Sep 2. doi: 10.1021/acsnano.5b02611.
Foiret J, Ferrara KW, “Spatial and Temporal Control of Hyperthermia Using Real Time Ultrasonic Thermal Strain Imaging with Motion Compensation, Phantom Study,” Public Library of Science One, PLoS One. 2015 Aug 5; 10(8): e0134938. doi: 10.1371/journal.pone.0134938.
Zhang H, Tam S, Ingham ES, Mahakian LM, Lai CY, Tumbale SK, Teesalu T, Hubbard NE, Borowsky AD, Ferrara KW, “Ultrasound molecular imaging of tumor angiogenesis with a neuropilin-1-targeted microbubble,” Biomaterials, 2015 July; 56: 104-13. doi: 10.1016/j.biomaterials.2015.03.043.
Fite BZ, Wong A, Liu Y, Mahakian LM, Tam SM, Aina O, Hubbard NE, Borowsky A, Cardiff RD, Dumont E, Ferrara KW, “Magnetic resonance imaging assessment of effective ablated volume following high intensity focused ultrasound,” Public Library of Science One, PLoS One. 2015 Mar 18; 10(3): e0120037. doi: 10.1371/journal.pone.0120037.
Seo JW, Mahakian LM, Tam S, Qin S, Ingham ES, Meares CF, Ferrara KW, “The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model,” Nuclear Medicine and Biology, Nucl Med Biol. 2015 Feb; 42(2): 155-63. doi: 10.1016/j.nucmedbio.2014.09.001.
2014
Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu J, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD, “Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis,” Proceedings of the National Academy of Sciences of the U S A, Proc Natl Acad Sci U S A (PNAS). 2014 Jul 14. pii: 201410432. doi: 10.1073/pnas.1410432111. PMID: 25024195. PMCID: PMC4121808.
Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock B, Zhang G, “ω-3 Polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer,” Prostaglandins & Other Lipid Mediators, Prostaglandins Other Lipid Mediat. 2014 Jul 11. doi:10.1016/j.prostaglandins.2014.07.002. [Epub ahead of print].
Dube N, Seo JW, Dong H, Shu JY, Lund R, Mahakian LM, Ferrara KW, Xu T, “Effect of Alkyl Length of Peptide-Polymer Amphiphile on Cargo Encapsulation Stability and Pharmacokinetics of 3-Helix Micelles,” Biomacromolecules, 2014 Jul 2. doi: 10.1021/bm5005788. PMID: 24988250. PMCID: PMC4130244. [Epub ahead of print].
Mahakian LM, Farwell DG, Zhang H, Seo JW, Poirier B, Tinling SP, Afify A, Haynam EM, Shaye D, Ferrara KW, “Comparison of PET imaging with 64Cu-liposomes and 18F-FDG in the 7,12–dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch model of oral dysplasia and squamous cell carcinoma,” Molecular Imaging and Biology, 2014 Apr; 16(2): 284-92. doi: 10.1007/s11307-013-0676-1.
Adamson RH, Clark JF, Radeva MY, Jiang Y, Kheirolomoom A, Ferrara KW, Curry FR, “Albumin modulates A1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect,” American Journal of Physiology: Heart and Circulatory Physiology, Am J Physiol Heart Circ Physiol. 2014 Apr 1; 306(7): H1011-7. doi: 10.1152/ajpheart.00829.2013.
Paoli EE, Ingham ES, Zhang H, Mahakian LM, Fite BZ, Gagnon MK, Tam S, Kheirolomoom A, Cardiff RD, Ferrara KW, “Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes,” Journal of Controlled Release, J Control Release. 2014 Mar 28; 178: 108-17. doi: 10.1016/j.jconrel.2014.01.005. PMID: 24434424. PMCID: PMC4079909.
Seo JW, Baek H, Mahakian LM, Kusunose J, Hamzah J, Ruoslahti E, Ferrara KW, “64Cu-Labeled LyP-1-Dendrimer for PET-CT Imaging of Atherosclerotic Plaque,” Bioconjugate Chemistry, Bioconjug Chem. 2014 Feb 19; 25(2): 231-9. doi: 10.1021/bc400347s. PMID: 24433095. PMCID: PMC4311647.
Lai CY, Kruse DE, Ferrara KW, Caskey CF, “Creation and characterization of an ultrasound and CT phantom for non-invasive ultrasound thermometry calibration,” IEEE transactions on biomedical engineering, IEEE Trans BME. 2014 Feb; 61(2): 502-512. doi: 10.1109/TBME.2013.2282775. PMID: 24107918. PMCID: PMC3990871.
Qin S, Fite BZ; Gagnon K, Curry FR, Thorsen F, Ferrara KW, “A physiological perspective on the use of imaging to assess the in vivo delivery of therapeutics,” Annals of Biomedical Engineering, Ann Biomed Eng. 2014 Feb; 42(2): 280-98. doi: 10.1007/s10439-013-0895-2. PMID: 24018607. PMCID: PMC3943857.
Lanza GM, Moonen C, Baker JR, Chang E, Cheng Z, Grodzinski P, Ferrara KW, Hynynen K, Kelloff G, Lee YK, Patri A, Sept D, Schnitzer JE, Wood B, Zhang M, Zheng G, Farahani K, “Assessing the barriers to image-guided drug delivery,” Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Jan; 6(1): 1-14. doi: 10.1002/wnan.1247.
Kusunose J, Gagnon MK, Seo JW, Ferrara KW, “Quantitation of nanoparticle accumulation in flow using optimized microfluidic chambers,” Journal of Drug Targeting. 2014 Jan; 22(1): 48-56. DOI: 10.3109/1061186X.2013.837468. PMID: 24079404. PMCID: PMC4004627.
2013
Son DJ, Kumar S, Takabe W, Kim CW, Ni CW, Alberts-Grill N, Jang I, Kim SO, Kim WK, Kang SW, Baker AH, Seo JW, Ferrara KW, Jo H, “The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis,” Nature Communications, Nat Commun. 2013 Dec 18; 4: 3000. doi: 10.1038/ncomms4000. PMID: 24346612. PMCID: PMC3923891.
Thorsen F, Fite B, Mahakian LM, Seo JW, Qin S, Harrison V, Johnson S, Ingham ES, Meade TJ, Caskey CF, Sundstrøm T, Harter P, Skaftnesmo KO, Ferrara KW, “Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases,” Journal of Controlled Release, J Control Release. 2013 Dec 28; 172(3): 812-22. doi: 10.1016/j.jconrel.2013.10.019. PMID: 24161382. PMCID: PMC3922207.
Dube N, Shu JY, Dong H, Seo JW, Ingham E, Kheirolomoom A, Chen PY, Forsayeth J, Bankiewicz K, Ferrara KW, Xu T, “Evaluation of Doxorubicin-loaded 3-Helix Micelles as Nanocarriers,” Biomacromolecules. 2013 Oct 14; 14(10): 3697-705. doi: 10.1021/Bm4010518. PMID: 24050265. PMCID: PMC3923314.
Kheirolomoom A, Lai CY, Ingham ES, Tam SM, Mahakian LM, Watson KD, Ferrara KW, “Complete regression of local cancer with minimal toxicity by multiple administrations of doxorubicin stabilized in temperature-sensitive liposomes combined with ultrasound-mediated hyperthermia,” Journal of Controlled Release, J Control Release. 2013 Nov 28; 172(1): 266-73. doi: 10.1016/j.jconrel.2013.08.019. PMID: 23994755. PMCID: PMC3938386.
Lai CY, Fite BZ, Ferrara, KW et al, “Ultrasonic enhancement of drug penetration in solid tumors,” Frontiers in Oncology, 2013; 3: 204. doi: 10.3389/fonc.2013.00204. PMCID: PMC3746679.
Lai CY, Kruse DE, Seo JW, Kheirolomoom A, Ferrara KW, “A phantom for visualization of three-dimensional drug release by ultrasound-induced mild hyperthermia,” Medical Physics, Med Phys. 2013 Aug; 40(8): 083301. doi: 10.1118/1.4813299. PMID: 23927360. PMCID: PMC3739833.
Hu X, Caskey CF, Mahakian LM, Kruse DE, Beegle JR, Declèves AE, Rychak JJ, Sutcliffe PL, Sharma K, Ferrara KW, “In vivo validation and 3D visualization of broadband ultrasound molecular imaging,” American Journal of Nuclear Medicine and Molecular Imaging, AJNMMI. 2013 Jul 10; 3(4): 336-49. PMID: 23901359. PMCID: PMC3715778.
Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD, “Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth and metastasis,” Proceedings of the National Academy of Sciences of the U S A, Proc Natl Acad Sci U S A (PNAS). 2013 Apr 16; 110(16): 6530-5. doi: 10.1073/pnas.1304321110. Epub 2013 Apr 3. PMCID: PMC3631682.
Malik ZA, Kott KS, Poe AJ, Kuo T, Chen L, Ferrara KW, Knowlton AA, “Cardiac myocyte exosomes: stability, HSP60, and proteomics,” American Journal of Physiology: Heart and circulatory physiology, Am J Physiol Heart Circ Physiol. 2013 Apr; 304(7): H954-65. Epub 2013 Feb 1. doi: 10.1152/ajpheart.00835.2012. PMID: 23376832. PMCID: PMC3625894.
Wong AW, Ormsby E, Zhang H, Seo JW, Mahakian LM, Caskey CF, Ferrara KW, “A comparison of image contrast with 64Cu-labeled long circulating liposomes and 18F-FDG in a murine model of mammary carcinoma,” American Journal of Nuclear Medicine and Molecular Imaging, Am J Nucl Med Mol Imaging. 2013; 3(1): 32-43. Epub 2013 Jan 5. PMID: 23342299. PMCID: PMC3545363.
Kusunose J, Zhang H, Gagnon MK, Pan T, Simon SI, Ferrara KW, “Microfluidic system for facilitated quantification of nanoparticle accumulation to cells under laminar flow,” Annals of Biomedical Engineering, Ann Biomed Eng. 2013 Jan; 41(1): 89-99. Epub 2012 Aug 2. doi: 10.1007/s10439-012-0634-0. PMID: 22855121. PMCID: PMC3505813.
2012
Zhang H, Li N, Sirish P, Mahakian L, Ingham E, Curry FR, Yamada S, Chiamvimonvat N, Ferrara KW, “The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium,” Journal of Controlled Release, J Control Release, in press. doi: 10.1016/j.jconrel.2012.06.038. PMID: 22776291. PMCID: PMC3552610.
Perng JK, Lee S, Kundu K, Caskey CF, Knight SF, Satir S, Ferrara KW, Taylor WR, Degertekin FL, Sorescu D, Murthy N, “Ultrasound imaging of oxidative stress in vivo with chemically-generated gas microbubbles,” Annals of Biomedical Engineering, Ann Biomed Eng. 2012 May 5. doi: 10.1007/s10439-012-0573-9. PMID: 22562306. PMCID: PMC4029424. [Epub ahead of print].
Dong H, Dube N, Shu JY, Seo JW, Mahakian LM, Ferrara KW, Xu T, “Long-Circulating 15 nm Micelles Based on Amphiphilic 3-Helix Peptide-PEG Conjugates,” ACS Nano. 2012 Jun 26; 6(6): 5320-9. Epub 2012 May 4. doi: 10.1021/nn301142r. PMID: 22545944. PMCID: PMC3531550.
Fite BZ, Liu Y, Kruse DE, Caskey CF, Walton JH, Lai CY, Mahakian LM, Larrat B, Dumont E, Ferrara KW, “Magnetic Resonance Thermometry at 7T for Real-Time Monitoring and Correction of Ultrasound Induced Mild Hyperthermia,” Public Library of Science One, PLoS ONE 7(4): e35509. doi:10.1371/journal.pone.0035509.
Hu, X, Kheirolomoom, A, Mahakian, LM, Beegle, JR, Kruse, DE, Lam, KS, Ferrara, KW, “Insonation of Targeted Microbubbles Produces Regions of Reduced Blood Flow within Tumor Vasculature,” Investigative Radiology, Invest Radiol. 2012 Jul; 47(7): 398-405. doi: 10.1097/RLI.0b013e31824bd237. PMID: 22659591.
Watson KD, Lai CY, Qin S, Kruse DE, Lin YC, Seo JW, Cardiff RD, Mahakian LM, Beegle J, Ingham ES, Curry FR, Reed RK, Ferrara KW, “Ultrasound increases nanoparticle delivery by reducing intratumoral pressure and increasing transport in epithelial and epithelial-mesenchymal transition tumors,” Cancer Research. 2012 Mar 15; 72(6): 1485-93. Epub 2012 Jan 26. doi: 10.1158/0008-5472.Can-11-3232. PMID: 22282664.
2011
Charles F. Caskey, Mario Hlawitschka, Shengping Qin, Lisa M. Mahakian, Robert D. Cardiff, John M. Boone, Katherine W. Ferrara, “An open environment CT-US fusion for tissue segmentation during interventional guidance,” Public Library of Science One, PLoS One, 2011; 6(11): e27372. Epub 2011 Nov 23. doi: 10.1371/journal.pone.0027372.
Mario Hlawitschka, Robert J. McGough, Katherine W. Ferrara, Dustin E. Kruse, “Fast Ultrasound Beam Prediction for Linear and Regular Two-dimensional Arrays,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 2011 Aug;58(9), 2001-12. doi: 10.1109/TUFFC.2011.2044. PMID: 21937338. PMCID: PMC3306819.
Caskey CF, Hu X, Ferrara KW, “Leveraging the power of ultrasound for therapeutic design and optimization,” Journal of Controlled Release, J Control Release. 2011 Dec 20; 156(3): 297-306. Epub 2011 Jul 30. doi: 10.1016/j.jconrel.2011.07.032.
Stephens D, Kruse D, Qin S, Ferrara K, “Design aspects of focal beams from high-intensity arrays,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 2011 Aug; 58(8): 1590-602. doi: 10.1109/TUFFC.2011.1986. PMID: 21859578. PMCID: PMC3174850.
Hamzah J, Kotamraju VR, Seo JW, Agemy L, Fogal V, Mahakian LM, Peters D, Roth L, Gagnon MK, Ferrara KW, Ruoslahti E, “Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice,” Proceedings of the National Academy of Sciences of the U S A, Proc Natl Acad Sci U S A (PNAS). 2011 Apr 26; 108(17): 7154-9. Epub 2011 Apr 11. doi: 10.1073/pnas.1104540108. PMID: 21482787. PMCID: PMC3084060.
Watson KD, Hu X, Lai CY, Lindfors HA, Hu-Lowe DD, Tuthill TA, Shalinsky DR, Ferrara KW, “Novel Ultrasound and DCE-MRI Analyses after Antiangiogenic Treatment with a Selective VEGF Receptor Inhibitor,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 2011 Jun; 37(6): 909-21. Epub 2011 Apr 30. doi: 10.1016/j.ultrasmedbio.2011.03.001. PMID: 21531499. PMCID: PMC3198831.
Kruse, DE, Stephens, DN, Lindfors, HA, Ingham, ES, Paoli, EE, and Ferrara, KW, “A radio-frequency coupling network for heating of citrate-coated gold nanoparticles for cancer therapy: design and analysis,” IEEE transactions on biomedical engineering, IEEE Trans BME. 2011 Jul; 58(7): 2002-12. Epub 2011 Mar 10. doi: 10.1109/TBME.2011.2124460. PMID: 21402506. PMCID: PMC3296119.
Andreozzi E, Seo JW, Ferrara K, Louie A, “A Novel Method to Label Solid Lipid Nanoparticles (SLNs) with Cu-64 for Positron Emission Tomography (PET) Imaging,” Bioconjugate Chemistry, Bioconjug Chem. 2011 Apr 20; 22(4): 808-18. Epub 2011 Mar 9. DOI: 10.1021/bc100478k. PMID: 21388194. PMCID: PMC3086097.
Seo JW, Qin S, Mahakian LM, Watson KD, Kheirolomoom A, Ferrara KW, “Positron emission tomography imaging of the stability of Cu-64 labeled dipalmitoyl and distearoyl lipids in liposomes,” Journal of Controlled Release, J Control Release. 2011 Apr 10; 151(1): 28-34. Epub 2011 Jan 15. doi: 10.1021/bc100478k. PMID: 21388194. PMCID: PMC3086097.
Anderson CR, Hu X, Zhang H, Tlaxca J, Declèves AE, Houghtaling R, Sharma K, Lawrence M, Ferrara KW, Rychak JJ, “Ultrasound Molecular Imaging of Tumor Angiogenesis with an Integrin Targeted Microbubble Contrast Agent,” Investigative Radiology, Invest Radiol. 2011 Apr; 46(4): 215-24. doi: 10.1097/RLI.0b013e3182034fed. PMID: 21343825. PMCID: PMC3075480.
Hu-Lowe DD, Chen E, Zhang L, Watson KD, Mancuso P, Lappin P, Wickman G, Chen JH, Wang J, Jiang X, Amundson K, Simon R, Erbersdobler A, Bergqvist S, Feng Z, Swanson TA, Simmons BH, Lippincott J, Casperson GF, Levin WJ, Gallo Stampino C, Shalinsky DR, Ferrara KW, Fiedler W, Bertolini F, “Targeting Activin Receptor-Like Kinase 1 (ALK1) Inhibits Angiogenesis and Tumorigenesis Through a Mechanism of Action Complementary to Anti-VEGF Therapies,” Cancer Research, Cancer Res. 2011 Jan 6. doi: 10.1158/0008-5472.CAN-10-1451. PMID: 21212415. PMCID: PMC3269003.
2010
Lai CY, Kruse DE, Caskey CF, Stephens DN, Sutcliffe P, Ferrara KW, “Noninvasive Thermometry Assisted by a Dual-Function Ultrasound Transducer for Mild Hyperthermia,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. vol. 57, no. 12, December 2010. doi: 10.1109/TUFFC.2010.1741. PMID: 21156363.
Kheirolomoom A, Mahakian LM, Lai CY, Lindfors HA, Seo JW, Paoli EE, Watson KD, Haynam EM, Ingham ES, Xing L, Cheng RH, Borowsky AD, Cardiff RD, Ferrara KW, “Copper-Doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity,” Molecular Pharmaceutics, Mol Pharm. 2010 Dec 6; 7(6): 1948-58. doi: 10.1021/Mp100245U. PMID: 20925429.
Rygh CB, Qin S, Seo JW, Mahakian LM, Zhang H, Adamson RH, Chen JQ, Borowsky AD, Cardiff RD, Reed RK, Curry FR, Ferrara KW, “Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET,” Clinical Cancer Research, Clin Cancer Res. 2010 Nov 24. doi: 10.1158/1078-0432.CCR-10-2049. PMID: 21106723. PMCID: PMC3107124.
Qin S, Ferrara KW, “A model for the dynamics of ultrasound contrast agents in vivo,” The Journal of the Acoustical Society of America, J Acoust Soc Am. 2010 Sep; 128(3): 1511-21. DOI: 10.1121/1.3409476. PMID: 20815486. PMCID: PMC2945756.
Seo JW, Mahakian LM, Kheirolomoom A, Zhang H, Meares CF, Ferdani R, Anderson CJ, Ferrara KW, “Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects,” Bioconjugate Chemistry, Bioconjug Chem. 2010 Jun 22. doi: 10.1021/bc100018n. PMID: 20568726. PMCID: PMC2943334.
Paoli EE, Kruse DE, Seo JW, Zhang H, Kheirolomoom A, Watson KD, Chiu P, Stahlberg H, Ferrara KW, “An optical and microPET assessment of thermally-sensitive liposome biodistribution in the Met-1 tumor model: Importance of formulation,” Journal of Controlled Release, J Control Release. 2010 Apr 2; 143(1): 13-22. doi: 10.1016/j.jconrel.2009.12.010. PMID: 20006659. PMCID: PMC2861564.
Qin S, Seo JW, Zhang H, Qi J, Curry FR, Ferrara KW, “An imaging-driven model for liposomal stability and circulation,” Molecular Pharmaceutics, Mol Pharm. 2010 Feb 1;7(1):12-21. doi: 10.1021/mp900122j. PMID: 19621944. PMCID: PMC2867051.
Kheirolomoom A, Kruse DE, Qin S, Watson KE, Lai CY, Young LJ, Cardiff RD, Ferrara KW, “Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system,” Journal of Controlled Release, J Control Release. 2010 Jan 25; 141(2): 128-36. Epub 2009 Sep 11. doi: 10.1016/j.jconrel.2009.08.029. PMID: 19748536. PMCID: PMC2815139.
Kruse DE, Lai CY, Stephens DN, Sutcliffe P, Paoli EE, Barnes SH, Ferrara KW, “Spatial and temporal-controlled tissue heating on a modified clinical ultrasound scanner for generating mild hyperthermia in tumors,” IEEE transactions on biomedical engineering, IEEE Trans Biomed Eng. 2010 Jan; 57(1): 155-66. doi: 10.1109/TBME.2009.2029703. PMID: 20064754. PMCID: PMC2892277.
Hu X, Zheng H, Kruse DE, Sutcliffe P, Stephens DN, Ferrara KW, “A sensitive TLRH targeted imaging technique for ultrasonic molecular imaging,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 2010; 57(2): 305-16. doi: 10.1109/tuffc.2010.1411. PMID: 20178897. PMCID: PMC2892275.
2009
Pollard RE, Dayton PA, Watson KD, Hu X, Guracar IM, Ferrara KW, “Motion corrected cadence CPS ultrasound for quantifying response to vasoactive drugs in a rat kidney model,” Urology. 2009 Sep; 74(3): 675-81. doi: 10.1016/j.urology.2009.01.086. PMID: 19589583. PMCID: PMC2735605.
Ferrara KW, Borden MA, Zhang H, “Lipid-shelled vehicles: engineering for ultrasound molecular imaging and drug delivery,” Accounts of Chemical Research, Acc Chem Res. 2009 Jul 21; 42(7): 881-92. doi: 10.1021/ar8002442. PMID: 19552457. PMCID: PMC2727628.
Caskey CF, Qin S, Dayton PA, Ferrara KW, “Microbubble tunneling in gel phantoms,” The Journal of the Acoustical Society of America, J Acoust Soc Am. 2009 May; 125(5): EL183-9. doi: 10.1121/1.3097679. PMID: 19425620. PMCID: PMC2736761.
Leu A, Stieger SM, Dayton P, Ferrara KW, Leach JK, “Angiogenic response to bioactive glass promotes bone healing in an irradiated calvarial defect,” Tissue Engineering Part A, Tissue Eng Part A. 2009 Apr; 15(4): 877-85. doi: 10.1089/ten.tea.2008.0018. PMID: 18795867. PMCID: PMC2992393.
Qin S, Caskey CF, Ferrara KW, “Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering,” Physics in Medicine & Biology, Phys Med Biol (PMB). 2009 Mar 21; 54(6): R27-57. DOI: 10.1088/0031-9155/54/6/R01. PMID: 19229096. PMCID: PMC2818980.
2008
Seo JW, Zhang H, Kukis DL, Meares CF, Ferrara KW, “A novel method to label preformed liposomes with 64Cu for positron emission tomography (PET) imaging,” Bioconjugate Chemistry, Bioconjug Chem. 2008 Dec; 19(12): 2577-84. doi: 10.1021/bc8002937. PMID: 18991368. PMCID: PMC2756669.
Tartis MS, Kruse DE, Zheng H, Zhang H, Kheirolomoom A, Marik J, Ferrara KW, Dynamic microPET imaging of ultrasound contrast agents and lipid delivery,” Journal of Controlled Release, J Control Release. 2008 Nov 12; 131(3): 160-6. doi: 10.1016/j.jconrel.2008.07.030. PMID: 18718854. PMCID: PMC2756153.
Stephens DN, Kruse DE, Ergun AS, Barnes S, Lu XM, Ferrara KW, “Efficient array design for sonotherapy,” Physics in Medicine & Biology, Phys Med Biol (PMB). 2008 Jul 21; 53(14): 3943-69. doi: 10.1088/0031-9155/53/14/014. PMID: 18591737. PMCID: PMC2570704.
Kruse DE, Mackanos MA, O’Connell-Rodwell CE, Contag CH, Ferrara KW, “Short-duration-focused ultrasound stimulation of Hsp70 expression in vivo,” Physics in Medicine & Biology, Phys Med Biol (PMB). 2008 Jul 7; 53(13): 3641-60. doi: 10.1088/0031-9155/53/13/017. PMID: 18562783.
Ferrara KW, “Driving delivery vehicles with ultrasound,” Advanced Drug Delivery Reviews, Adv Drug Deliv Rev. 2008 Jun 30; 60(10): 1097-102. DOI: 10.1016/j.addr.2008.03.002. PMID: 18479775. PMCID: PMC2811088.
Qin S, Kruse DE, Ferrara KW, “Transmitted ultrasound pressure variation in micro blood vessel phantoms,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 2008 Jun; 34(6): 1014-20. doi: 10.1016/j.ultrasmedbio.2007.11.021. PMID: 18395962.
Zhang H, Kusunose J, Kheirolomoom A, Seo JW, Qi J, Watson KD, Lindfors HA, Ruoslahti E, Sutcliffe JL, Ferrara KW, “Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model,” Biomaterials. 2008 Apr; 29(12): 1976-88. doi: 10.1016/j.biomaterials.2007.12.033. PMID: 18255141. PMCID: PMC2475513.
Borden MA, Zhang H, Gillies RJ, Dayton PA, Ferrara KW, “A stimulus-responsive contrast agent for ultrasound molecular imaging,” Biomaterials. 2008 Feb; 29(5): 597-606. doi: 10.1016/j.biomaterials.2007.10.011. PMID: 17977595. PMCID: PMC2266628.
Zheng H, Kruse DE, Stephens DN, Ferrara KW, Sutcliffe P, Gardner E, “A sensitive ultrasonic imaging method for targeted contrast microbubble detection,” Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Conf Proc IEEE Eng Med Biol Soc (EMBC). 2008; 2008: 5290-3. doi: 10.1109/IEMBS.2008.4650408. PMID: 19163911.
Stieger SM, Dayton PA, Borden MA, Caskey CF, Griffey SM, Wisner ER, Ferrara KW, “Imaging of angiogenesis using Cadence contrast pulse sequencing and targeted contrast agents,” Contrast Media & Molecular Imaging, Contrast Media Mol Imaging. 2008 Jan; 3(1): 9-18. doi: 10.1002/cmmi.224. PMID: 18335479.
2007
Mark A. Borden, Charles Caskey, Erica Little, Robert J. Gillies & Katherine W. Ferrara, “DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles,” Langmuir, epub August 3, 2007. doi: 10.1021/La7009034. PMID: 17665937.
Charles Caskey, Susanne Stieger, Shengping Qin, Paul Dayton, Katherine W. Ferrara, “Direct observations of ultrasound microbubble contrast agent interaction with the microvessel wall,” The Journal of the Acoustical Society of America, J Acoust Soc Am. 122(2) August, 2007, 1191-1200. doi: 10.1121/1.2747204. PMID: 17672665.
Katherine Ferrara, Rachel Pollard, Mark Borden, “Ultrasound Microbubble Contrast Agents: Fundamentals and Application to Gene and Drug Delivery,” Annual Review of Biomedical Engineering, Vol. 9: 415-447. doi: 10.1146/annurev.bioeng.8.061505.095852. PMID: 17651012. (Volume publication date August 2007).
Azadeh Kheirolomoom, Katherine W. Ferrara, “Cholesterol transport from liposomal delivery vehicles,” Biomaterials, Jun 5, 2007. doi: 10.1016/j.biomaterials.2007.06.008. PMID: 17610949. PMCID: PMC2043118.
Shengping Qin, Katherine W. Ferrara, “The natural frequency of nonlinear oscillation of ultrasound contrast agents in microvessels,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. Epub ahead of print, May 1, 2007. doi: 10.1016/j.ultrasmedbio.2006.12.009. PMID: 17478030. PMCID: PMC2637385.
Susanne M. Stieger, Charles F. Caskey, S. Qin, Roger H. Adamson, Fitz-Roy E. Curry, Erik R. Wisner, Katherine W. Ferrara, “Enhancement of Vascular Permeability with Low-Frequency Contrast-enhanced Ultrasound in the Chorioallantoic Membrane Model,” Radiology, 2007 April; 243(1): 112-121. doi: 10.1148/radiol.2431060167.
Shukui Zhao, Dustin E. Kruse, Katherine W. Ferrara, and Paul A. Dayton, “Selective imaging of adherent targeted ultrasound contrast agents,” Physics in Medicine & Biology, Phys Med Biol (PMB). 52 (2007): 2055-2072. doi: 10.1088/0031-9155/52/8/002. PMID: 17404455.
Yang Sun, Dustin E. Kruse, Katherine W. Ferrara, “Contrast imaging with chirped excitation,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. March 2007,; 54(3): 520-529. doi: 10.1109/Tuffc.2007.275. PMID: 17375821.
Azadeh Kheirolomoom, Paul A.Dayton, Aaron F.H. Lum, Erika Little, Eric E. Paoli, Hairong Zheng, Katherine W.Ferrara, “Acoustically-active microbubbles conjugated to liposomes: Characterization of a proposed drug delivery vehicle,” Journal of Controlled Release, J Control Release. 2006 Dec 23. doi: 10.1016/J.Jconrel.2006.12.015. PMID: 17300849. PMCID: PMC2662343.
Jan Marik, Michaelann S. Tartis, Hua Zhang, Jennifer Y. Fung, Azadeh Kheirolomoom, Julie L. Sutcliffe, Katherine W. Ferrara, “Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP),” Nuclear Medicine and Biology, Nucl Med Biol. 2007 Feb; 34(2): 165-171. doi: 10.1016/j.nucmedbio.2006.12.004. PMID: 17307124.
Pollard RE, Broumas AR, Wisner ER, Vekich SV, Ferrara KW, “Quantitative contrast enhanced ultrasound and ct assessment of tumor response to antiangiogenic therapy in rats,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 2007 Feb; 33(2): 235-245. doi: 10.1016/j.ultrasmedbio.2006.07.036.
2006
Michaelann Shortencarier Tartis, Jennifer McCallan, Aaron F.H. Lum, Rachel LaBell, Susanne M. Stieger, Terry O. Matsunaga and Katherine W. Ferrara, “Therapeutic effects of paclitaxel-containing ultrasound contrast agents,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. Volume 32, Issue 11, November 2006, Pages 1771-1780. doi: 10.1016/j.ultrasmedbio.2006.03.017.
Shukui Zhao, Dustin E. Kruse, Katherine W. Ferrara, and Paul A. Dayton, ““Acoustic response from adherent targeted contrast agents,” The Journal of the Acoustical Society of America, J Acoust Soc Am, (Jasa Electronic Letters). 120(6), Dec. 2006, Epublished Oct. 2006, pp. EL63-EL69. doi: 10.1121/1.2364303.
Shengping Qin and Katherine W Ferrara, “Acoustic response of compliable microvessels containing ultrasound contrast agents,” Physics in Medicine & Biology, Phys Med Biol (PMB). 51 (2006) 5065-5088, September, 2006. doi:10.1088/0031-9155/51/20/001.
Paul Dayton, Shukui Zhao, Susannah Bloch, Patricia A Schumann, Kim Penrose, Terry O Matsunaga, Reena Zutshi, Alexander Doinikov and Katherine W Ferrara, “Application of ultrasound to selectively localize nanodroplets for targeted imaging and therapy,” Molecular Imaging, 5(3), July 2006. doi: 10.2310/7290.2006.00019. PMID: 16954031.
Mark A Borden, Melissa R Sarantos, Susanne M Stieger, Scott I Simon, Katherine W Ferrara and Paul Dayton, “Ultrasound Radiation Force Modulates Ligand Availability on Targeted Contrast Agents,” Molecular Imaging, 5(3), July 2006. doi: 10.2310/7290.2006.00016. PMID: 16954028.
R. Pollard, R. Yunis, D. Kueltz, P. Martin, S. Griffey, K. Ferrara, “Ultrasonic detection and characterization of polycystic kidney disease in a mouse model,” Comparative Medicine, 2006 Jun; 56(3):215-21.
Yang Sun, Shukui Zhao, Paul A. Dayton and Katherine W. Ferrara, “Observation of contrast agent response to chirp insonation with a simultaneous optical-acoustical system,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC, June 2006, 53(6), 1130-1137. doi: 10.1109/Tuffc.2006.1642511. PMID: 16846145.
Stieger SM, Bloch SH, Foreman O, Wisner ER, Ferrara KW, Dayton P, “Ultrasound assessment of angiogenesis in a Matrigel model in rats,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. May 2006; 32(5): 673-81. doi: 10.1016/J.Ultrasmedbio.2005.12.008. PMID: 16677927.
A. Louie, J. Izatt, Katherine Ferrara, “Biomedical Imaging Graduate Curricula and Courses: Report from the 2005 Whitaker Biomedical Engineering Educational Summit,” Annals of Biomedical Engineering, Ann Biomed Eng. 2006 Feb; 34(2): 239-47. Epub 2006 Feb 16. doi: 10.1007/S10439-005-9033-0. PMID: 16482417.
Mark A. Borden, Josette Ricker, Nelly Tsvetkova, Marjorie Longo, Paul A.Dayton & Katherine W. Ferrara, “Lateral Phase Separation in Lipid-Coated Microbubbles,” Langmuir, 2006 Apr 25; 22(9): 4291-4297. doi: 10.1021/La052841V. PMID: 16618177.
Charles F. Caskey, Dustin E. Kruse, Paul A. Dayton, Tyler K. Kitano, Katherine W. Ferrara, “Microbubble Oscillation in Tubes with Diameters of 12, 25, and 195 Microns,” Applied Physics Letters, 88, 033902, Epub ahead of print, 2006. doi: 10.1063/1.2164392.
2005
Aaron F H Lum, Mark A Borden, Paul A Dayton, Dustin E Kruse, Scott I Simon, Katherine W Ferrara, “Ultrasound Radiation Force Enables Targeted Deposition of Model Drug Carriers Loaded on Microbubbles,” Journal of Controlled Release, J Control Release. Epub ahead of print, 2005. doi: 10.1016/J.Jconrel.2005.11.006. PMID: 16380187.
Shukui Zhao, Katherine W. Ferrara, and Paul A. Dayton, “Asymmetric oscillation of adherent targeted ultrasound contrast agents,” Applied Physics Letters, 87, 134103-1-3, (2005). doi: 10.1063/1.2061872. PMID: 16755307.
M.A. Borden, D.E. Kruse, C.F. Caskey, Shukui Zhao, P.A. Dayton, K.W. Ferrara, “Influence of Lipid Shell Physiochemical Properties on Ultrasound-Induced Microbubble Destruction,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 52(11), November 2005, 1992-2002. doi: 10.1109/TUFFC.2005.1561668. PMID: 16422411.
Y. Sun, D. Kruse, P. Dayton, K. Ferrara, “High-Frequency Dynamics of Ultrasound Contrast Agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 25(11), November 2005, 1981-91. doi: 10.1109/Tuffc.2005.1561667. PMID: 16422410.
Dustin Kruse, K. Ferrara, ““A New Imaging Strategy Utilizing Wideband Transient Response of Ultrasound Contrast Agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 52(8), August 2005, 1320-9. doi: 10.1109/TUFFC.2005.1509790. PMID: 16245601.
S. H. Bloch, R. E. Short, K. W. Ferrara, E. R. Wisner, “The effect of size on the acoustic response of polymer shelled contrast agents,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 31(3): 439-44, 2005. doi: 10.1016/J.Ultrasmedbio.2004.12.016. PMID: 15749568.
Amy R. Broumas, Rachel E. Pollard, Susannah H. Bloch, Erik R. Wisner, Steven Griffey, and Katherine W. Ferrara, “Contrast-enhanced computed tomography and ultrasound for the evaluation of tumor blood flow,” Investigative Radiology, 40(3): 134-147, 2005. doi: 10.1097/01.Rli.0000152833.35744.7F. PMID: 15714088.
Y.T. Hu, Shengping Qin, Ting Hu, Katherine W. Ferrara, Qing Jiang, “Asymmetric oscillation of cavitation bubbles in a microvessel and its implications upon mechanisms of clinical vessel injury in shock-wave lithotripsy,” International Journal of Non-Linear Mechanics, 40(2-3): 341-350, 2005. doi: 10.1016/J.Ijnonlinmec.2004.06.007.
2004
S. H. Bloch, P. A. Dayton, and K. W. Ferrara, “Targeted imaging using ultrasound contrast agents,” IEEE Engineering in Medicine and Biology Magazine, 23(5): 18-29, 2004. DOI: 10.1109/Memb.2004.1360405. PMID: 15565796.
S. H. Bloch, M. Wan, P. A. Dayton, and K. W. Ferrara, “Optical observation of lipid- and polymer-shelled ultrasound microbubble contrast agents,” Applied Physics Letters, 84(4):631-3, 2004. doi: 10.1063/1.1643544.
P. A. Dayton, D. P. Pearson, J. Clark, S. I. Simon, P. Schumann, R. Zutshi, T. O. Matsunaga, and K. W. Ferrara, “Ultrasonic analysis of peptide- and antibody-targeted microbubble contrast agents for molecular imaging of αvβ3-expressing cells,” Molecular Imaging, 3(2): 125-134, 2004. PMID: 15296677.
D. N. Patel, S. H. Bloch, P. A. Dayton, and K. W. Ferrara, “Acoustic signatures of submicron contrast agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 51(3):293-301, 2004. doi: 10.1109/TUFFC.2004.1320785. PMID: 15128216.
R. E. Pollard, T. C. Garcia, S. M. Stieger, K. W. Ferrara, A. R. Sadlowski, and E. R. Wisner, “Quantitative evaluation of peripheral tumor perfusion and permeability using contrast enhanced computed tomography,” Investigative Radiology, 39(6): 340-9, 2004. doi: 10.1097/01Rli.0000124456.82985.35. PMID: 15167100.
M. J. Shortencarier, P. A. Dayton, S. H. Bloch, P. A. Schumann, T. O. Matsunaga, and K. W. Ferrara, “A method for Radiation-Force Localized Drug Delivery Using Gas-Filled Lipospheres,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 51(7): 822-31, 2004. doi:10.1109/Tuffc.2004.1320741. PMID: 15301001.
Chih-Kuang Yeh, Katherine W. Ferrara, and Dustin E. Kruse, “High resolution functional vascular assessment with ultrasound,” IEEE Transactions on Medical Imaging, 23(10): 1263-75, 2004. doi: 10.1109/Tmi.2004.834614. PMID: 15493694.
S. Zhao, M. Borden, S. H. Bloch, D. Kruse, K. W. Ferrara, and P. A. Dayton, “Radiation force assisted targeting facilitates ultrasonic molecular imaging,” Molecular Imaging, 3(3): 135-148, 2004. PMID: 15530249. PMCID: PMC1356635.
2003
J. S. Allen, D. E. Kruse, P. A. Dayton, and K. W. Ferrara, “Effect of coupled oscillations on microbubble behavior,” Journal of the Acoustical Society of America, J Acoust Soc Am. 114(3):1678-90, 2003. doi: 10.1121/1.1600721. PMID: 14514221.
J. E. Chomas, R. E. Pollard, A. R. Sadlowski, S. M. Griffey, E. R. Wisner, and K. W. Ferrara, “Contrast-enhanced US of microcirculation of superficially implanted tumors in rats,” Radiology, 229(2): 439-46, 2003. doi: 10.1148/radiol.2292020536. PMID: 14526091.
E. R. Wisner, K. W. Ferrara, R. E. Short, T. B. Ottoboni, J. D. Gabe, and D. Patel, “Sentinel node detection using contrast-enhanced power Doppler ultrasound lymphography,” Investigative Radiology, 38(6):358-365, 2003. doi: 10.1097/01.rli.0000065423.05038.88. PMID: 12908703.
2002
J. S. Allen, D. J. May, and K. W. Ferrara, “Dynamics of therapeutic ultrasound contrast agents,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 28(6): 805-16, 2002. doi: 10.1016/s0301-5629(02)00522-7. PMID: 12113793.
J. Chomas, P. Dayton, D. May, and K. Ferrara, “Nondestructive subharmonic imaging”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 49(7): 883-92, 2002. doi: 10.1109/tuffc.2002.1020158. PMID: 12152942.
P. A. Dayton, J. S. Allen, and K. W. Ferrara, “The magnitude of radiation force on ultrasound contrast agents,” Journal of the Acoustical Society of America, J Acoust Soc Am. 112(5 Pt 1): 2183-92, 2002. doi: 10.1121/1.1509428. PMID: 12430830.
P. A. Dayton and K. W. Ferrara, “Targeted imaging using ultrasound,” Journal of Magnetic Resonance Imaging, 16(4):362-77, 2002. doi: 10.1002/jmri.10173. PMID: 12353252.
D. E. Kruse and K. W. Ferrara, “A new high resolution color flow system using an eigendecomposition-based adaptive filter for clutter rejection,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 49(12): 1739-54, 2002. doi: 10.1109/Tuffc.2002.1159852. PMID: 12546154.
D. J. May, J. S. Allen, and K. W. Ferrara, “Dynamics and fragmentation of thick-shelled microbubbles,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 49(10): 1400-10, 2002. doi: 10.1109/tuffc.2002.1041081. PMID: 12403141.
D. Patel, P. Dayton, J. Gut, E. Wisner, and K. W. Ferrara, “Optical and acoustical interrogation of submicron contrast agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 49(12): 1641-51, 2002. doi: 10.1109/TUFFC.2002.1159844.
R. E. Pollard, A. R. Sadlowski, S. H. Bloch, L. Murray, E. R. Wisner, S. Griffey, and K. W. Ferrara, “Contrast-assisted destruction-replenishment ultrasound for the assessment of tumor microvasculature in a rat model,” Technology in Cancer Research and Treatment, 1(6): 459-70, 2002. doi: 10.1177/153303460200100606. PMID: 12625773.
R. H. Silverman, R. Ursea, D. Kruse, K. W. Ferrara, M. J. Rondeau, and D. J. Coleman, “Ultrasound measurement of the effect of temperature on microperfusion in the eye,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 28(11-12): 1413-9, 2002. doi: 10.1016/s0301-5629(02)00694-4. PMID: 12498936.
E. R. Wisner, K. Ferrara, J. D. Gabe, D. Patel, T. G. Nyland, R. E. Short, and T. B. Ottoboni, “Contrast enhanced intermittent power Doppler ultrasound with sub-micron bubbles for sentinel node detection,” Academic Radiology, 9(Suppl 2): S389-91, 2002. doi: 10.1016/s1076-6332(03)80241-6. PMID: 12188286.
2001
J. S. Allen, D. E. Kruse, and K. W. Ferrara, “Shell waves and acoustic scattering from ultrasound contrast agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 48(2): 409-18, 2001. doi: 10.1109/58.911723. PMID: 11370354.
J. E. Chomas, P. Dayton, J. Allen, K. Morgan, and K. W. Ferrara, “Mechanisms of contrast agent destruction,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 48(1): 232-48, 2001. doi: 10.1109/58.896136. PMID: 11367791.
J. E. Chomas, P. Dayton, D. May, and K. Ferrara, “Threshold of fragmentation for ultrasonic contrast agents,” Journal of Biomedical Optics, 6(2): 141-50, 2001. doi: 10.1117/1.1352752. PMID: 11375723.
P. A. Dayton, J. E. Chomas, A. F. Lum, J. S. Allen, J. R. Lindner, S. I. Simon, and K. W. Ferrara, “Optical and acoustical dynamics of microbubble contrast agents inside neutrophils,” Biophysical Journal, 80(3):1547-56, 2001. DOI: 10.1016/S0006-3495(01)76127-9. PMID: 11222315.
2000
J. E. Chomas, P. A. Dayton, D. May, J. Allen, A. Klibanov, and K. Ferrara, “Optical observation of contrast agent destruction,” Applied Physics Letters, 77(7): 1056-8, 2000. doi: 10.1063/1.1287519.
K. W. Ferrara, C. R. Merritt, P. N. Burns, F. S. Foster, R. F. Mattrey, and S. A. Wickline, “Evaluation of tumor angiogenesis with US: imaging, Doppler, and contrast agents,” Academic Radiology, 7(10):824-39, 2000. doi: 10.1016/S1076-6332(00)80631-5. PMID: 11048880.
D. Kruse and K. Ferrara, “Color flow mapping,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 26(Suppl 1):S16-8, 2000. doi: 10.1016/S0301-5629(00)00154-X.
J. R. Lindner, P. A. Dayton, M. P. Coggins, K. Ley, J. Song, K. Ferrara, and S. Kaul, “Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles,” Circulation, 102(5):531-8, 2000. doi: 10.1161/01.Cir.102.5.531. PMID: 10920065.
K. E. Morgan, J. S. Allen, P. A. Dayton, J. E. Chomas, A. L. Klibaov, and K. W. Ferrara, “Experimental and theoretical evaluation of microbubble behavior: effect of transmitted phase and bubble size,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 47(6): 1494-509, 2000. doi: 10.1109/58.883539.
1999
P. Dayton, A. Klibanov, G. Brandenburger, and K. Ferrara, “Acoustic radiation force in vivo: a mechanism to assist targeting of microbubbles,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 25(8): 1195-201, 1999. doi: 10.1016/S0301-5629(99)00062-9. PMID: 10576262.
P. A. Dayton, K. E. Morgan, A. L. Klibanov, G. H. Brandenburger, and K. W. Ferrara, “Optical and acoustical observations of the effects of ultrasound on contrast agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 46(1): 220-32, 1999. doi: 10.1109/58.741536. PMID: 18238417.
R. H. Silverman, D. E. Kruse, D. J. Coleman, and K. W. Ferrara, “High-resolution ultrasonic imaging of blood flow in the anterior segment of the eye,” Investigative Opthalmology & Visual Science, 40(7): 1373-81, 1999. PMID: 10359319.
1998
A. L. Klibanov, K. W. Ferrara, M. S. Hughes, J. H. Wible, Jr., J. K. Wojdyla, P. A. Dayton, K. E. Morgan, and G. H. Brandenburger, “Direct video-microscopic observation of the dynamic effects of medical ultrasound on ultrasound contrast microspheres,” Investigative Radiology, 33(12): 863-70, 1998. doi: 10.1097/00004424-199812000-00004. PMID: 9851820.
D. E. Kruse, R. H. Silverman, R. J. Fornaris, D. J. Coleman, and K. W. Ferrara, “A swept-scanning mode for estimation of blood velocity in the microvasculature,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 45(6): 1437-40, 1998. doi: 10.1109/58.738282. PMID: 18249990.
K. E. Morgan, M. Averkiou, and K. Ferrara, The effect of the phase of transmission on contrast agent echoes,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 45(4): 872-5, 1998. DOI: 10.1109/58.710539. PMID: 18244239.
K. E. Morgan, P. A. Dayton, D. E. Kruse, A. L. Klibanov, G. H. Brandenburger, and K. W. Ferrara, “Changes in the echoes from ultrasonic contrast agents with imaging parameters,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 45(6): 1537-48, 1998.
B. G. Zagar, R. J. Fornaris, and K. W. Ferrara, “Ultrasonic mapping of the microvasculature: signal alignment,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 24(6): 809-24, 1998. doi: 10.1016/S0301-5629(98)00042-8. PMID: 9740383.
1997
P. A. Dayton, K. E. Morgan, A. L. Klibanov, G. Brandenburger, K. R. Nightingale, and K. W. Ferrara, “A preliminary evaluation of the effects of primary and secondary radiation forces on acoustic contrast agents,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 44(6): 1264-77, 1997. doi: 10.1109/58.656630.
A. I. el-Fallah, M. B. Plantec, and K. W. Ferrara, “Ultrasonic measurement of breast tissue motion and the implications for velocity estimation,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 23(7): 1047-57, 1997. doi: 10.1016/S0301-5629(97)00079-3. PMID: 9330448.
K. Ferrara and G. DeAngelis, “Color flow mapping [Review],” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 23(3): 321-45, 1997. doi: 10.1016/S0301-5629(96)00216-5. PMID: 9160902.
pre-1997
K. W. Ferrara, B. Zagar, J. Sokil-Melgar, and V. R. Algazi, “High resolution 3D color flow mapping: applied to the assessment of breast vasculature,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 22(3): 293-304, 1996. doi: 10.1016/0301-5629(95)02060-8. PMID: 8783461.
K. W. Ferrara, B. G. Zager, J. B. Sokil-Melgar, R. H. Silverman, and I. M. Aslanidis, “Estimation of blood velocity with high frequency ultrasound,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on UFFC. 43(1): 149-57, 1996. doi: 10.1109/58.484474.
K. W. Ferrara, M. Ostromogilsky, S. Rosenberg, and J. Sokil-Melgar, “Parameter mapping for the detection of disturbed blood flow,” Ultrasound in Medicine & Biology, Ultrasound Med Biol. 21(4): 517-25, 1995. doi: 10.1016/0301-5629(94)00152-4. PMID: 7571144.
